Values differed insignificantly. Inhospital mortality was higher among patients receiving 10 g
Values differed insignificantly. Inhospital mortality was higher among patients receiving 10 g/kg/minute dopamine or more. Among 31 patients receiving less than 10 g/kg/minute dopamine 16 (51.6 ) died, while among those 31 receiving 10 g/kg/minute or PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/18930858 more 27 (87.1 ) died. This was a significant difference according to the Pearson 2 criterion (2 = 9.182, P = 0.002). Conclusions Initiation of aortic counterpulsation should be considered as soon as possible, while the patient with acute myocardial infarction is treated with low doses of vasopressors.was significantly lower in female patients (P <0.01). In the 75 years group, the rate of physical labors was significantly higher in female patients (P <0.01); the rate of mental labors was significantly lower in female patients (P <0.01). Conclusions Compared with male patients, female patients with AMI were older, and type 2 diabetes mellitus and hypertension probably played more important roles in female patients. A higher rate of physical labors and a lower rate of mental labors in female patients probably contribute to prevent them from AMI.P154 Influence of arterial pressure on tissue 2′,3′-cGAMP perfusion in septic shockE Tishkov, O Bukaev Moscow State Medical University, Moscow, Russian Federation Critical Care 2009, 13(Suppl 1):P154 (doi: 10.1186/cc7318) Introduction The aim of this study was to measure the effects of increasing mean arterial pressure (MAP) on systemic oxygen metabolism and regional tissue perfusion in septic shock. Methods Twenty patients with the diagnosis of septic shock who required pressor agents to maintain a MAP 65 mmHg after fluid resuscitation to a pulmonary artery occlusion pressure (PAOP) 12 mmHg were included. Norepinephrine was titrated to MAPs of 65 mmHg, 75 mmHg and 85 mmHg in 20 patients with septic shock. Results At each level of MAP, hemodynamic parameters (heart rate, PAOP, cardiac index, left ventricular stroke work index, and systemic vascular resistance index), metabolic parameters (oxygen delivery, oxygen consumption, blood lactate), and regional perfusion parameters (gastric mucosal PCO2, skin capillary blood flow and red blood cell velocity, urine output) were measured. Increasing the MAP from 65 to 85 mmHg with norepinephrine resulted in increases in cardiac index from 3.5 ?0.4 l/min/m2 to 5.0 ?0.5 l/min/m2 (P < 0.03). Blood lactate was 3.5 ?0.8 mEq/l at a MAP of 65 mmHg and 3.0 ?0.8 mEq/l at 85 mmHg (P = NS). The gradient between arterial PCO2 and gastric intramucosal PCO2 was 11 ?3 mmHg (1.5 ?0.3 kPa) at a MAP of 65 mmHg and 15 ?3 mmHg at 85 mmHg (2.0 ?0.3 kPa, P = NS). Urine output at 65 mmHg was 40 ?10 ml/hour and was 45 ?12 ml/hour at 85 mmHg (P = NS). As the MAP was raised, there were no significant changes in skin capillary blood flow or red blood cell velocity. Conclusions Increasing the MAP from 65 mmHg to 85 mmHg with norepinephrine does not significantly affect systemic oxygen metabolism, skin microcirculatory blood flow, urine output, or splanchnic perfusion.P153 Study of risk factors for female patients with acute myocardial infarctionH Fu1, Y Zhao2 Rehabilitation Research Center, Beijing, China; 2Gerontic Cardiovascular Disease Institution, Beijing, China Critical Care 2009, 13(Suppl 1):P153 (doi: 10.1186/cc7317)1ChinaIntroduction Acute myocardial infarction (AMI) is one of the most common cardiovascular emergencies. Female patients have different features to male patients. The objective of our study was to analyze risk factors for female pa.